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Free Radical Therapy Blog » 2008» March

Archive for March, 2008

Cartilage and Chondroitin Can Be Helpful in Detox, But at a Price…

Sunday, March 30th, 2008

FRT requires that you deal with the acid/base balance and the other four common denominators of health before tackling the sixth of these events, oxidative stress. Where oxidative stress is due to a fat-soluble toxin, proper regulation of the CyP450 is required. To satisfy Phase II of biotransformation, cartilage and chondroitin can become the source of glucuronidation. If the body chooses to derive its glucuronidation through this route you are in the midst of connective tissue breakdown, which is the fifth of our common denominators of health. Cartilage and chondroitin sulfate contain uronic acid residues that are linked to D-glucosamine. Heparin, a natural component of connective tissue, is similarly constructed. As the body disassembles itself (a common event when protein status is inadequate) oxidation of circulating glucose with uronic acid results in the glucuronic acid that is required for the conjugation seen in the Phase II of the biotransformation of fat-soluble toxins to a water-soluble forms, which can be excreted through the urine or gut. So, FRT helps you avoid making your source of glucuronidation your healthy joints. You would otherwise expect joint pain, where (yes), you could reach for chondroitin sulfate, and likely get some relief. Yet, through FRT you get at the broader cause while you avoid becoming another statistic of potential product contamination.

Heparin Deaths Reveal How Chondroitin Sulfate Can Become a Poison

Sunday, March 30th, 2008

As China becomes a more common source of pharmaceuticals, the risk of death and disability rises from contaminated products. In an article that recently appeared in Chemical and Engineering News (March 24, 2008), science writer Jyllian Kemsley informed that the FDA has uncovered the cause of the recent deaths from Heparin (a drug commonly used in hospitals). It was due to an unnatural form of chondroitin sulfate, which like heparin is a a variably sulfated glycosaminoglycan. While chondroitin sulfate used in food supplements is generally derived from a natural source, cartilage, the form used in the deadly heparin was chemically modified with additional sulfate groups. Hypersulfated chondroitin sulfate does not appear in nature, and so it had to have been intentionally synthesized by someone who wanted to do much harm, which happened.

Such occurrences are not new.  Just a year ago pet food from China was busy causing the death of pets, due to the addition of the chemical, melamine. Melamine, a product of plastics, caused the assessment of protein in pet foods to look really high, but in reality it was a toxin that possessed no protein properties.

So, these days we have more problems with the question, what do I do for this or that, than simply following a disease model. We must also make certain that our health and food products undergo reliable testing. To help with this our government is now insisting that the Chinese government allow our own FDA inspectors to become part of the inspection process of what goes into the goods shipped to the rest of the world. Bottom line: FRT is the answer to most every health question. Too, if you don’t know the formula you had best get acquainted with just where your suppliers are getting their products.

What Do I Do For…?

Sunday, March 30th, 2008

People are always calling to ask what to do for arthritis or some other disease condition. Such questions arise from being far too familiar with the disease model system of health. It’s the approach that doctors are taught, and it’s the language that they’ve trained their patients to ask. Not surprising, most nutrition-based programs are carried out the same way. People who think they are into health look for the answer they want in a disease-based manner. Yet it can really get you into trouble.

If your answer to the arthritis question is “chondroitin sulfate and glucosamine”, you certainly would be providing a useful disease-model based answer where your answer is aimed at dealing with the symptom. Yet, if you really want to get at the root cause and then perhaps improve many other areas of health with the same brush stroke then FRT will be your answer.